Table of normal puppy development from birth to 6 weeks of age
What is Normal	Week 1	Week 2	Weeks 3-4	Weeks 5-6
Temperature, Rectal	96-98F	96-99F	100F	100-101F
Ambient Temperature	75-80F	70-80F	70-75F	65-75F
Heart Rate	200-240bpm	200-240bpm	160-200bpm	Varies with breed
Respiratory Rate	15-35 per min	15-35 per min	15-25 per min	15-25 per min
Mucous Membrane Colour/CRT	Pink to red if recently nursed	Pink 1 second	Pink 1 second	Pink 1 second
Urine Colour	Very pale yellow	Very pale yellow	Pale yellow	Pale to moderate yellow
Weight	May loose up to 10% in first 3 days Birth weight: Toys 100-200g, Medium 300-400g, Large 400-500g, Giant 700g.	Gaining 5-10% daily, many double birth weight by day 10. Calculate weight gain of 2-4 gm/day/kg anticipated adult weight.	Calculate weight gain of 2-4 gm/day/kg anticipated adult weight.	Calculate weight gain of 4-4 gm/day/kg anticipated adult weight. Giant and large breeds gain at a faster rate than smaller breeds.
Activity	Sleeps & eats 90% of the time, twitch while sleeping.	Sleeps & eats 90% of the time, twitch while sleeping.	Beginning to crawl, then stand & walk by day 21. Start to play when eyes open. Can sit.	Walking, climbing, playing, may bark, begin to explore environment, mouthing. Normal postural reflexes.
Attitude	Quiet, cry infrequently.	Quiet.	Quiet, more active.	Start to develop ‘personalities’
Vision & Hearing	No vision but may blink at bright light. No hearing.	None to limited vision and hearing, may by waxy discharge.	Vision blurry. Respond to sound & startle reflex develops.	Approaching full vision and hearing.
Teeth	None	None	Deciduous incisors & canines erupt.	Deciduous premolars erupt.
Breeders Interaction	Assure pups are nursing. Supplement if necessary. Daily temp, weight, urine & stool character. Begin early neurological stimulation day 2-16.	Assure pups are nursing. Supplement if necessary. Daily temp, weight, urine & stool character. Continue early neurological stimulation day 2-16.	Continue to assure pups are thriving, begin to enrich environment by variation of toys, surfaces. Begin weaning.	Continue to assure pups are thriving, continue to enrich environment. Lots of human interaction for socialisation.
Food & Water	Nursing only. If supplementing, 60ml/lb/24hours divided by 12. Fed every 2 hours.	Nursing only. If supplementing, 70ml/lb/24 hours divided by 8, fed every 3 hours.	Offer water, then gruel to start weaning. If supplementing, 90ml/lb/24 hours divided by 6. Fed every 4 hours.	Teething. Many pups weaned, on full food and water, some still nurse for social interaction.